"The heart can be an assassin. Homicide Detective Billy Able knows that from experience. Fresh from solving Memphis's most sensational murder case, Billy and his ambitious new partner, Frankie Malone, are called to a bizarre crime scene on the outskirts of town. A high-society attorney has been murdered while dressed in a wedding gown. Billy is shocked to discover he has a very personal connection to the victim. When the attorney's death exposes illegal...

As a new generation of Ables learn to navigate their powers and what it means to be a superhero, a mysterious disease begins to wipe out the older population of heroes, and three generations of Ables must unite to uncover the secret lab that holds the cure.